학술논문
Prevalence and Associated Factors of Diabetic Retinopathy in a Russian Population. The Ural Eye and Medical Study
ORIGINAL RESEARCH
ORIGINAL RESEARCH
Document Type
Academic Journal
Author
Bikbov, Mukharram M.; Gilmanshin, Timur R.; Zainullin, Rinat M.; Kazakbaeva, Gyulli M.; Nuriyev, Ildar F.; Zaynetdinov, Artur F.; Panda-Jonas, Songhomitrra; Bikbova, Guzel M.; Rakhimova, Ellina M.; Rusakova, Iulia A.; Khalimov, Timur A.; Safullina, Kamila R.; Fakhretdinova, Albina A.; Tuliakova, Azaliia M.; Gizzatov, Ainur V.; Jonas, Jost B.
Source
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. December 31, 2021, Vol. 14, p4723, 12 p.
Subject
Language
English
ISSN
1178-7007
Abstract
Plain Language Summary A multiethnic population in Russia with an age of 40+ years had a prevalence of diabetic retinopathy of 1.9%. Individuals with shorter (hyperopic) eyes and a higher [...]
Aim: To assess prevalence and associated factors of diabetic retinopathy (DR) in a Russian population. Methods: Out of 7328 eligible individuals, the population-based cross-sectional Ural Eye and Medical Study included 5899 (80.5%) individuals aged 40+ years, who underwent a detailed medical and ophthalmological examination. Using ocular fundus photographs and optical coherence tomographic images, we assessed prevalence and degree of DR in 5105 participants. Results: DR was present in 99/5105 individuals (1.9%; 95% confidence interval [CI]: 1.6, 2.3). Its prevalence increased from 6/657 (1.0%; 95% CI: 0.2, 1.6) in the age group of 45-50 years to 24/680 (3.5%; 95% CI: 2.1, 4.9) in the age group of 65-70 years, and decreased to 3/153 (2.0%; 95% CI: 0.00, 4.2) in the age group of 80+ years. DR prevalence within the 577 (11.4%; 95% CI: 10.5, 12.2) individuals with diabetes was 99/577 (17.2%; 95% CI: 14.1, 20.2). DR was the cause for moderate-to-severe vision impairment (best corrected visual acuity Conclusion: In this urban and rural Russian population aged 40+ years, DR prevalence was relatively low (1.9%; 95% CI: 1.6, 2.3), showed an inverted U-shaped association with age, and in a cross-sectional study design it was associated with shorter axial length and higher estimated cerebrospinal fluid pressure. Keywords: diabetic retinopathy, cerebrospinal fluid pressure, myopia, axial length, blindness, ural eye and medical study
Aim: To assess prevalence and associated factors of diabetic retinopathy (DR) in a Russian population. Methods: Out of 7328 eligible individuals, the population-based cross-sectional Ural Eye and Medical Study included 5899 (80.5%) individuals aged 40+ years, who underwent a detailed medical and ophthalmological examination. Using ocular fundus photographs and optical coherence tomographic images, we assessed prevalence and degree of DR in 5105 participants. Results: DR was present in 99/5105 individuals (1.9%; 95% confidence interval [CI]: 1.6, 2.3). Its prevalence increased from 6/657 (1.0%; 95% CI: 0.2, 1.6) in the age group of 45-50 years to 24/680 (3.5%; 95% CI: 2.1, 4.9) in the age group of 65-70 years, and decreased to 3/153 (2.0%; 95% CI: 0.00, 4.2) in the age group of 80+ years. DR prevalence within the 577 (11.4%; 95% CI: 10.5, 12.2) individuals with diabetes was 99/577 (17.2%; 95% CI: 14.1, 20.2). DR was the cause for moderate-to-severe vision impairment (best corrected visual acuity Conclusion: In this urban and rural Russian population aged 40+ years, DR prevalence was relatively low (1.9%; 95% CI: 1.6, 2.3), showed an inverted U-shaped association with age, and in a cross-sectional study design it was associated with shorter axial length and higher estimated cerebrospinal fluid pressure. Keywords: diabetic retinopathy, cerebrospinal fluid pressure, myopia, axial length, blindness, ural eye and medical study