부산대학교 도서관

Background: Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia due to either insulin deficiency or resistance or both. Hyperglycemia induces tissue damage through mitochondrial superoxide production, affecting retina, glomerulus, and neurons. It requires continuing medical care and ongoing self-care management to prevent and delay acute and long-term complications. Therefore, our study was designed to assess glycemic control and diabetes complications among diabetes patients attending at University of Gondar Hospital. Materials and methods: A cross-sectional study was conducted among DM patients attending at University of Gondar Hospital diabetes follow-up clinic during February-March 2017. Five milliliters of blood was collected using aseptic technique. Levels of fasting blood sugar (FBS), triglycerides, and cholesterol were measured using MINDRAY BS-200E machine. FBS [greater than or equal to]152 mg/dL was taken as poor glycemic control. Binary and multivariable logistic regression models were used to evaluate associated risk factors for the outcome variable. A P-value of Result: Three hundred sixty-seven diabetes patients were included in this study. About 222 (60.5%) of them had poor glycemic control (FBS [greater than or equal to]152 mg/dL). The proportion of poor glycemic control was slightly higher among type 1 DM patients (61.4%) than type 2 DM patients (59.8%). Age [greater than or equal to]65 years (adjusted odds ratio [AOR]: 0.070; 95% CI: 0.016-0.308), being divorced (AOR: 0.226; 95% CI: 0.064-0.8000), and increased waist circumference (AOR: 0.361: 95% CI: 0.181-0.720) were factors that significantly reduce poor glycemic control. Diabetes complications were slightly higher in insulin- and tablet-only users, 72.5% and 64.5%, respectively. DM complications were also higher in patients who had poor glycemic control (61/222) and type 2 diabetes (78 [37.3%]). Conclusion: Prevalence of poor glycemic control and DM complications was high, which indicate that appropriate intervention is required to improve glycemic control and prevent or control complications among DM patients. Keywords: diabetes mellitus, glycemic control, diabetes complications, Ethiopia
Introduction Diabetes mellitus (DM) is a group of metabolic disorders characterized by hyperglycemia due to failure in secretion, action, or both of insulin. (1) Chronic noncommunicable diseases are becoming considerable [...]