학술논문
Anti-CD7 CAR T cells for T-ALL: impressive early-stage efficacy
Document Type
Report
Author
Source
Nature Reviews Clinical Oncology. November, 2021, Vol. 18 Issue 11, p677, 2 p.
Subject
Language
English
ISSN
1759-4774
Abstract
Chimeric antigen receptor (CAR) T cells have remarkable efficacy in patients with B cell acute lymphoblastic leukaemia (ALL), but have not been successful to date in patients with T cell ALL (T-ALL). Now, data from Pan and colleagues demonstrate the safety and impressive short-term efficacy of allogeneic donor-derived anti-CD7 CAR T cells in an early-phase clinical trial involving patients with relapsed and/or refractory T-ALL.
Author(s): David T. Teachey [sup.1] [sup.2] , Stephen P. Hunger [sup.1] [sup.2] Author Affiliations: (1) Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, USA (2) The Center for Childhood [...]
Author(s): David T. Teachey [sup.1] [sup.2] , Stephen P. Hunger [sup.1] [sup.2] Author Affiliations: (1) Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, USA (2) The Center for Childhood [...]