학술논문

Basal cell carcinoma-not always the 'good guy': Case report of a life-threatening basosquamous carcinoma and review of the literature
Document Type
Clinical report
Source
Experimental and Therapeutic Medicine. October 2021, Vol. 22 Issue 4
Subject
Romania
Language
English
ISSN
1792-0981
Abstract
Introduction Basosquamous carcinoma (BSC), also called metatypical basal cell carcinoma, is a subtype of basal cell carcinoma (BCC), displaying histological features of both BCC and squamous cell carcinoma (SCC) (1). [...]
Cutaneous basosquamous carcinoma is a variant of basal cell carcinoma that is characterized by histopathological features of both basal and squamous cell carcinoma. Due to its local invasiveness, high frequency of recurrence, and its metastatic potential, it is considered to be one of the most aggressive subtypes of basal cell carcinoma. We present the case of an 81-year-old male who was admitted to the hospital with incessant hemorrhage arising from a cutaneous tumor that later proved to be a basosquamous carcinoma. Due to the COVID-19 pandemic at the time, the patient did not seek medical attention as soon as the bleeding was observed, although he did present when the symptom increased in intensity and became incessant. To our knowledge, this is the first case report of a cutaneous basosquamous carcinoma that presents with a massive life-threatening hemorrhage tumor, thus endangering the patient's life. The clinical and histopathological features, the behavior and the treatment of cutaneous basosquamous carcinoma are further reviewed in this article. Key words: basal cell carcinoma, basosquamous carcinoma, life-threatening, hemorrhage, COVID-19 pandemic