학술논문
Sex disparities in patients with symptomatic severe aortic stenosis
Document Type
Academic Journal
Author
Source
American Heart Journal. July 2021, Vol. 237, 116
Subject
Language
English
ISSN
0002-8703
Abstract
Background We evaluated whether there is equitable distribution across sexes of treatment and outcomes for aortic valve replacement (AVR), via surgical (SAVR) or transcatheter (TAVR) methods, in symptomatic severe aortic stenosis (ssAS) patients. Methods Using de-identified data, we identified 43,822 patients with ssAS (2008-2016). Multivariate competing risk models were used to determine the likelihood of any AVR, while accounting for the competing risk of death. Association between sex and 1-year mortality, stratified by AVR status, was evaluated using multivariate Cox regression models with AVR as a time-dependent variable. Results Among patients with ssAS, 20,986 (47.9%) were female. Females were older (median age 81 vs. 78, P Conclusions Treatment rates for ssAS patients remain suboptimal with disparities in female treatment.