학술논문

Determining Risk Factors for Dengue Fever Severity in Jeddah City, a Case-Control Study (2017)
ORIGINAL PAPER
Document Type
Report
Source
Polish Journal of Microbiology. September 2020, Vol. 69 Issue 3, p331, 7 p.
Subject
Saudi Arabia
Language
English
ISSN
1733-1331
Abstract
Introduction Dengue fever (DF) is a mosquito-borne disease transmitted by dengue virus, causing a flu-like illness that may develop into a possibly fatal complication leading to severe dengue (WHO 2017). [...]
Dengue fever is a major public health problem in Saudi Arabia. Unfortunately, preventive strategies are still deficient. It can progress to severe and lethal forms, and available knowledge does not allow early prediction of which cases of dengue fever (DF) will progress to dengue hemorrhagic fever (DHF). The aim of this study was to evaluate the host and viral factors that could play a role in the progression of severe dengue cases in the frame of the revised 2009 WHO classification. Data were compiled from the Jeddah Dengue Fever Operation Room (DFOR) in the Maden Al-Fahd primary healthcare center in Jeddah. An unmatched case-control study was conducted on 123 severe cases, and 245 controls (non-severe cases) diagnosed during 2014-2016. Risk factors for severe dengue fever were secondary infection (p = 0.02), and co-morbidities, particularly diabetes and hypertension (p Key words: Dengue fever, viral infection, case control, risk factors