부산대학교 도서관

Keywords: Increased ICP; MRI; optic nerve sheath; point-of-care ultrasound ABSTRACT BACKGROUND AND PURPOSE Ultrasound (US) measurement of the optic nerve sheath diameter (ONSD) and optic nerve diameter (OND) is a method frequently used to screen for an increased intracranial pressure. The aim of this study was to assess the accuracy of US measurements of ONSD and OND, when compared to magnetic resonance imaging (MRI) measurements as the criterion standard. METHODS In this prospective, single-institution study, orbital US was performed for those patients requiring an emergent brain MRI. ONSD and OND of both eyes were measured in the axial and coronal planes in straight gaze by US. ONSD and OND from brain and orbital MRI were measured by two neuroradiologists. Correlation and agreement between readings were assessed using Pearson's correlations. RESULTS Eighty-two patients met inclusion criteria. The mean axial and coronal ONSD in the MRI examinations was 5.6 and 5.7 mm at 3-5.9 mm behind the globe, respectively. The mean ONSD from the US measurements was 6.22 and 5.52 mm in the axial and coronal planes, respectively. The mean OND in US examinations was 4.31 mm (axial) and 3.68 mm (coronal). Axial versus coronal measurements of ONSD had a modest correlation in US assessment with an r.sup.2 of .385 (P < .001) but there were no correlations between any of the US and MRI measurements. CONCLUSIONS In measuring ONSD and OND, US measurements showed a modest correlation between axial and coronal measurements, but no concordance was found between US and MRI in our setting. Article Note: Acknowledgment and Disclosure: The authors would like to thank emergency medicine residents, research associates, and staff at the Departments of Emergency Medicine and Radiology at the George Washington University Hospital in Washington DC. Special thanks to Drs Melissa McCarthy, Pouya Gharahdaghi, William Denq, Mary Graham, Sigrid Nasser, Ty Nichols, and Paige Kulie. This is a non-funded study, with no compensation or honoraria for participation, consulting, or conducting the study. Resources required for this project were provided by institutional departmental funds at the George Washington University, Department of Emergency Medicine, with NO particular budgeting allocated to this project. The authors do NOT have a financial interest or relationship to disclose regarding this research project. Byline: Hamid Shokoohi, Matthew Pyle, Evan Kuhl, Michael A. Loesche, Aakshit Goyal, Maxine A. LeSaux, Keith S. Boniface, M. Reza Taheri