학술논문
Prevalence of chronic kidney disease and its associated factors in Malaysia; findings from a nationwide population-based cross-sectional study
Document Type
Report
Author
Saminathan, Thamil Arasu; Hooi, Lai Seong; Mohd Yusoff, Muhammad Fadhli; Ong, Loke Meng; Bavanandan, Sunita; Rodzlan Hasani, Wan Shakira; Tan, Esther Zhao Zhi; Wong, Irene; Rifin, Halizah Mat; Robert, Tania Gayle; Ismail, Hasimah; Wong, Norazizah Ibrahim; Ahmad, Ghazali; Ambak, Rashidah; Othman, Fatimah; Abd Hamid, Hamizatul Akmal; Aris, Tahir
Source
BMC Nephrology. August 14, 2020, Vol. 21 Issue 1
Subject
Language
English
ISSN
1471-2369
Abstract
Author(s): Thamil Arasu Saminathan[sup.1] , Lai Seong Hooi[sup.2] , Muhammad Fadhli Mohd Yusoff[sup.1] , Loke Meng Ong[sup.3] , Sunita Bavanandan[sup.4] , Wan Shakira Rodzlan Hasani[sup.1] , Esther Zhao Zhi Tan[sup.5] [...]
Background The prevalence of chronic kidney disease (CKD) in Malaysia was 9.07% in 2011. We aim to determine the current CKD prevalence in Malaysia and its associated risk factors. Methods A population-based study was conducted on a total of 890 respondents who were representative of the adult population in Malaysia, i.e., aged [greater than or equai to]18 years old. Respondents were randomly selected using a stratified cluster method. The estimated glomerular filtration rate (eGFR) was estimated from calibrated serum creatinine using the CKD-EPI equation. CKD was defined as eGFR < 60 ml/min/1.73m.sup.2 or the presence of persistent albuminuria if eGFR [greater than or equai to]60 ml/min/1.73m.sup.2. Results Our study shows that the prevalence of CKD in Malaysia was 15.48% (95% CI: 12.30, 19.31) in 2018, an increase compared to the year 2011 when the prevalence of CKD was 9.07%. An estimated 3.85% had stage 1 CKD, 4.82% had stage 2 CKD, and 6.48% had stage 3 CKD, while 0.33% had stage 4-5 CKD. Hypertension (aOR 3.72), diabetes mellitus (aOR 3.32), increasing BMI (aOR 1.06), and increasing age (aOR 1.06) were significantly associated with CKD. Conclusion Our study has shown that CKD has become one of the leading public health issues in Malaysia. Thus, there is an urgent need to screen for CKD and prevent its progression, associated morbidity, and mortality at the national level. Keywords: Chronic kidney disease, Prevalence, Associated factors, Adults, Malaysia
Background The prevalence of chronic kidney disease (CKD) in Malaysia was 9.07% in 2011. We aim to determine the current CKD prevalence in Malaysia and its associated risk factors. Methods A population-based study was conducted on a total of 890 respondents who were representative of the adult population in Malaysia, i.e., aged [greater than or equai to]18 years old. Respondents were randomly selected using a stratified cluster method. The estimated glomerular filtration rate (eGFR) was estimated from calibrated serum creatinine using the CKD-EPI equation. CKD was defined as eGFR < 60 ml/min/1.73m.sup.2 or the presence of persistent albuminuria if eGFR [greater than or equai to]60 ml/min/1.73m.sup.2. Results Our study shows that the prevalence of CKD in Malaysia was 15.48% (95% CI: 12.30, 19.31) in 2018, an increase compared to the year 2011 when the prevalence of CKD was 9.07%. An estimated 3.85% had stage 1 CKD, 4.82% had stage 2 CKD, and 6.48% had stage 3 CKD, while 0.33% had stage 4-5 CKD. Hypertension (aOR 3.72), diabetes mellitus (aOR 3.32), increasing BMI (aOR 1.06), and increasing age (aOR 1.06) were significantly associated with CKD. Conclusion Our study has shown that CKD has become one of the leading public health issues in Malaysia. Thus, there is an urgent need to screen for CKD and prevent its progression, associated morbidity, and mortality at the national level. Keywords: Chronic kidney disease, Prevalence, Associated factors, Adults, Malaysia