학술논문
Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study
Document Type
Clinical report
Source
Lipids in Health and Disease. August 15, 2020, Vol. 19 Issue 1
Subject
Language
English
ISSN
1476-511X
Abstract
Author(s): Qiaofeng Song[sup.1], Xiaoxue Liu[sup.1], Wenhua Zhou[sup.1], Shouling Wu[sup.2] and Xizhu Wang[sup.1] Introduction Short or long sleep durations have been reported to be associated with a higher risk of diabetes [...]
Background To explore the associations between sleep duration and abnormalities in serum lipid levels in a Chinese population. Methods A prospective study was conducted with 34,260 participants from the general Chinese population. Sleep duration was categorized as [less than or equai to]5, 6, 7, 8 or [greater than or equai to] 9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults (2016). The Cox proportional hazards model was used to assess the association between sleep duration and dyslipidemia. Results Compared with a 7 h sleep duration, long sleep duration ([greater than or equai to]9 h) was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (hazard ratio (HR): 1.24; 95% CI: 1.12-1.38). In subgroup analyses, the positive association between long sleep duration and low HDL-C level in men and in the different age groups was more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population (P-interaction> 0.05). Conclusions These findings suggest that long sleep duration is associated with low HDL-C level among the Kailuan community population. Keywords: Sleep duration, Dyslipidemia, High-density lipoprotein cholesterol, Low-density lipoprotein cholesterol, Prospective cohort
Background To explore the associations between sleep duration and abnormalities in serum lipid levels in a Chinese population. Methods A prospective study was conducted with 34,260 participants from the general Chinese population. Sleep duration was categorized as [less than or equai to]5, 6, 7, 8 or [greater than or equai to] 9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults (2016). The Cox proportional hazards model was used to assess the association between sleep duration and dyslipidemia. Results Compared with a 7 h sleep duration, long sleep duration ([greater than or equai to]9 h) was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (hazard ratio (HR): 1.24; 95% CI: 1.12-1.38). In subgroup analyses, the positive association between long sleep duration and low HDL-C level in men and in the different age groups was more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population (P-interaction> 0.05). Conclusions These findings suggest that long sleep duration is associated with low HDL-C level among the Kailuan community population. Keywords: Sleep duration, Dyslipidemia, High-density lipoprotein cholesterol, Low-density lipoprotein cholesterol, Prospective cohort