학술논문
The target organ damage in hypertension--the link to worse prognosis of COV1D19 patients
Document Type
Academic Journal
Source
Journal of Hypertension Research. April-June 2020, Vol. 6 Issue 2, p43, 5 p.
Subject
Language
English
Abstract
Introduction From the report of the first case of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SaRS-CoV2) in December 2019 from Wuhan China, by June 1st 2020, 8.596.037 [...]
From the report of the first case of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV2) in December 2019 from Wuhan China, by June 1st 2020, 8.596.037 confirmed cases worldwide have been reported. Hypertension (HT) appears to increase the severity of COVID-19 and mortality risk both directly and indirectly. The immune system plays an important role in hypertension and hypertension-mediated organ damage. The invasion of SARS-CoV2 into the organism of a hypertensive patient, which already has a deleterious inflammatory immune response, can therefore more easily drive a quicker and exacerbated inflammatory response, leading more often, through cytokine storm, to severe ARDS forms, with worse prognosis for COVID-19 hypertensive patients. Keywords: Hypertension, COVID-19, SARS-CoV2, Inflammation, Prognosis.
From the report of the first case of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV2) in December 2019 from Wuhan China, by June 1st 2020, 8.596.037 confirmed cases worldwide have been reported. Hypertension (HT) appears to increase the severity of COVID-19 and mortality risk both directly and indirectly. The immune system plays an important role in hypertension and hypertension-mediated organ damage. The invasion of SARS-CoV2 into the organism of a hypertensive patient, which already has a deleterious inflammatory immune response, can therefore more easily drive a quicker and exacerbated inflammatory response, leading more often, through cytokine storm, to severe ARDS forms, with worse prognosis for COVID-19 hypertensive patients. Keywords: Hypertension, COVID-19, SARS-CoV2, Inflammation, Prognosis.