학술논문
Prevalence and Associated Factors of Pseudoexfoliation in a Russian Population: The Ural Eye and Medical Study
Document Type
Clinical report
Author
Bikbov, Mukharram M.; Zainullin, Rinat M.; Gilmanshin, Timur R.; Kazakbaeva, Gyulli M.; Yakupova, Dilya F.; Nuriev, Ildar F.; Zaynetdinov, Artur F.; Khalimov, Timur A.; Panda-Jonas, Songhomitra; Uzianbaeva, Yulia V.; Rakhimova, Ellina M.; Rusakova, Iulia A.; Salavatova, Venera F.; Arslangareeva, Inga I.; Bikbova, Guzel M.; Nikitin, Nikolay A.; Jonas, Jost B.
Source
American Journal of Ophthalmology. Feb 2020, Vol. 210, 158
Subject
Language
English
ISSN
0002-9394
Abstract
Purpose To assess the prevalence of pseudoexfoliation (PEX) and its associations in a Russian population. Design Population-based cross-sectional study. Methods Setting: Ufa capital of Bashkortostan, Russia and a rural region in Bashkortostan. Participants the Ural Eye and Medical Study included 5,899 (80.5%) of 7,328 eligible individuals (mean age, 59.0 [plus or minus] 10.7 years old; range, 40-94 years). Observation procedures: as part of an ophthalmological and general examination, presence and degree of PEX was assessed using slit-lamp biomicroscopy after medical pupillary dilation. Main outcome measurements: PEX prevalence. Results After excluding pseudophakic and aphakic individuals, the study included 5,451 (92.4%) participants. PEX prevalence (3.6%; 95% confidence interval [CI]:3.1-4.1), increased from 0.5% (95% CI, 0.1-0.9) in individuals 40 to Conclusions In this typical, ethnically mixed, population from Russia with an age of 40+ years, PEX prevalence (3.6%; 95% CI, 3.1-4.1) was associated with older age, Russian ethnicity, higher intraocular pressure and open-angle glaucoma. It was independent of any systemic parameter including diabetes, arterial hypertension, previous cardiovascular and cerebrovascular diseases and dementia.