학술논문

Nasopharyngeal carriage of Streptococcus pneumoniae and antimicrobial susceptibility pattern among school children in South Ethiopia: post-vaccination era
Document Type
Academic Journal
Source
BMC Research Notes. May 29, 2019, Vol. 12 Issue 1
Subject
Ethiopia
Language
English
ISSN
1756-0500
Abstract
Objective The aim of this study was to investigate nasopharyngeal carriage rate and antibiotic susceptibility patterns of Streptococcus pneumoniae among school children. Results Three hundred eleven (43.8%) became culture positive for S. pneumoniae. The carriage rate among children, 3-5 years old was 62.5%, which was higher than the carriage rate of 38.6% among 6-13 years old children. Age [less than or equai to] 5 years and co-sleeping with siblings remained significantly associated with S. pneumoniae carriage. 155 (49.8%) of the isolates were resistant to co-trimoxazole, 152 (48.9%) of the isolates were resistant to tetracycline, and 88 (28.3%) of isolates were resistant to oxacillin. Multi drug resistant S. pneumoniae was observed in 90 (28.9%) of isolates. There is high prevalence of S. pneumoniae in primary school children in our study area. Relatively high carriage rate of resistance to oxacillin, tetracycline and co-trimoxazole were observed. These findings provide baseline data for future studies to further compare pneumococcal carriage rates and antibiotic resistance patterns. Keywords: Nasopharyngeal, Carriage, S. pneumoniae, Sodo Zuria Woreda, Antibiotic, School children
Author(s): Fiseha Wadilo Wada[sup.1] , Efrata Girma Tufa[sup.2] , Tezera Moshago Berheto[sup.4] and Fithamlak Bisetegen Solomon[sup.3] Introduction World health organization (WHO) estimates that ~ 1.6 million people, including up to [...]