학술논문

Analysis of the oxidized low density lipoprotein receptor 1 gene as a potential marker for carcass quality traits in Qinchuan cattle
Document Type
Report
Source
Asian - Australasian Journal of Animal Sciences. January, 2019, Vol. 32 Issue 1, p58, 5 p.
Subject
Low density lipoprotein receptors -- Research
Cattle carcasses -- Research
Meat quality -- Research
Genetic research
DNA sequencing
Biodiversity
Single nucleotide polymorphisms
Genes
Low density lipoproteins
Genetic polymorphisms
DNA
Language
English
ISSN
1011-2367
Abstract
Objective: The oxidized low density lipoprotein receptor 1 (OLR1) gene plays an important role in the degradation of oxidized low-density lipoprotein and adipocyte proliferation in mammals. For this reason, we aimed at investigating the association of OLR1 gene polymorphisms with carcass quality traits in Chinese Qinchuan cattle.Methods: The single nucleotide polymorphism (SNP) was identified in the 3' untranslated region of bovine OLR1 gene by DNA sequencing. In addition, the haplotype frequency and linkage disequilibrium estimates of three SNPs were evaluated in 520 individuals.Results: Results indicated that the studied three SNPs were within the range of moderate genetic diversity (0.25< polymorphism information contentConclusion: Based on our results, we believe that the OLR1 gene could be a strong candidate gene for influencing carcass quality traits in Qinchuan cattle.Keywords: Carcass Quality Traits; Qinchuan Cattle; Association Analysis; Oxidized Low-density Lipoprotein Receptor 1 Gene
INTRODUCTIONIn China, Qinchuan cattle (Bos taurus) are generally considered as efficient converters of poor quality roughage to meat [1]. However, the carcass quality traits, i.e., back fat thickness, loin muscle [...]