학술논문
Common and emergent factors associated with hypertension control in Romania. Data from SEPHAR II Study
Original Article
Original Article
Document Type
Survey
Source
Journal of Hypertension Research. Jan-March 2016, Vol. 2 Issue 1, p19, 8 p.
Subject
Language
English
Abstract
IntroductionArterial hypertension was assigned the leading risk factor by Global Burden of Disease Study in 2010, responsible for 9.4 million deaths each year [1, 2]. Despite an impressive arsenal of [...]
Romania is an East European country with high mortality rates for ischemic heart and cerebrovascular diseases largely attributable to an increased level of uncontrolled hypertension. We aimed to analyze the data of SEPHAR II epidemiological study in order to identify the factors associated with treatment control in Romanian hypertensives. A total of 1975 subjects, selected on the base of stratified proportional sampling and consented to participate in the study, were evaluated during the two study visits. Hypertension was diagnosed according to current ESH-ESC guidelines (> 140/80 mmHg). High blood pressure (BP) variability was defined as visit-to-visit standard deviation (s.d.) of systolic blood pressure (SBP) situated in the 4th percentile with values [greater than or equal to] 8.49 mmHg (Q4_SBP_s.d.). Arterial stiffness recordings were realized with an oscillometric device (Medexpert Arteriograph IrDA). According to the multivariate analysis for the validation of parameters associated with lack of BP control were found significant: a low level of education [OR=2.86; 95% confidence interval (CI) 1.84-4.45, p 3 drugs, not including a diuretic [OR=1.91; 95% CI 0.95-3.84, p 3 drug associations including a diuretic and are launching the attention of the effects of arterial stiffness and SBP variability on BP levels under antihypertensive treatment.Keywords: arterial hypertension, blood pressure control, survey
Romania is an East European country with high mortality rates for ischemic heart and cerebrovascular diseases largely attributable to an increased level of uncontrolled hypertension. We aimed to analyze the data of SEPHAR II epidemiological study in order to identify the factors associated with treatment control in Romanian hypertensives. A total of 1975 subjects, selected on the base of stratified proportional sampling and consented to participate in the study, were evaluated during the two study visits. Hypertension was diagnosed according to current ESH-ESC guidelines (> 140/80 mmHg). High blood pressure (BP) variability was defined as visit-to-visit standard deviation (s.d.) of systolic blood pressure (SBP) situated in the 4th percentile with values [greater than or equal to] 8.49 mmHg (Q4_SBP_s.d.). Arterial stiffness recordings were realized with an oscillometric device (Medexpert Arteriograph IrDA). According to the multivariate analysis for the validation of parameters associated with lack of BP control were found significant: a low level of education [OR=2.86; 95% confidence interval (CI) 1.84-4.45, p 3 drugs, not including a diuretic [OR=1.91; 95% CI 0.95-3.84, p 3 drug associations including a diuretic and are launching the attention of the effects of arterial stiffness and SBP variability on BP levels under antihypertensive treatment.Keywords: arterial hypertension, blood pressure control, survey