학술논문

Lorazepam for the prevention of recurrent seizures related to alcohol
Document Type
Academic Journal
Source
The New England Journal of Medicine. March 25, 1999, Vol. 340 Issue 12, p915, 5 p.
Subject
Prevention
Evaluation
Care and treatment
Seizures (Medicine) -- Prevention
Lorazepam -- Evaluation
Alcoholics -- Care and treatment
Language
ISSN
0028-4793
Abstract
The drug lorazepam appears to be beneficial in preventing seizures caused by alcohol. Emergency physicians randomly assigned 229 alcoholics admitted to the ER for seizures to take a single dose of lorazepam or a placebo. Within six hours, 24% of the placebo group had a second seizure compared to 3% of the lorazepam group. Members of the placebo group were twice as likely to be admitted to the hospital as the lorazepam group. Even after discharge, those in the placebo group were more likely to have another seizure.