학술논문
Fatal Histoplasma capsulation mitral endocarditis in a French patient treated for rheumatoid arthritis
Document Type
Disease/Disorder overview
Author
Source
Mycopathologia. March 2012, Vol. 173 Issue 2-3, p183, 4 p.
Subject
Language
English
ISSN
0301-486X
Abstract
Introduction Histoplasma capsulatum (teleomorph, Ajellomyces capsulatus) is a dimorphic fungus with a worldwide distribution as a saprobe. Its mycelial form is usually found in soil containing large amounts of bird [...]
Histoplasmosis is an infectious disease caused by the inhalation of Histoplasma capsulatum spores, a fungus encountered in many diverse areas around the world. Although this infection is often asymptomatic, it may become dramatic in immunocompromised patients. In November 2005, an endocarditis due to Histoplasma capsulatum was diagnosed in a French woman treated for rheumatoid arthritis and who hadtraveledtoSouthAmerica 2 years earlier. We confirmed the biological diagnosis by mycological, serological, and histological methods. In spite of receiving the appropriate treatment, the patient died 3 months later of cardiac insufficiency. We report here this additional case of Histoplasma endocarditis, by hoping to help rapid and accurate diagnosis of such infections in their early stages of development, in non-endemic areas. Keywords Histoplasma capsulatum * Endocarditis * Travel * Diagnosis
Histoplasmosis is an infectious disease caused by the inhalation of Histoplasma capsulatum spores, a fungus encountered in many diverse areas around the world. Although this infection is often asymptomatic, it may become dramatic in immunocompromised patients. In November 2005, an endocarditis due to Histoplasma capsulatum was diagnosed in a French woman treated for rheumatoid arthritis and who hadtraveledtoSouthAmerica 2 years earlier. We confirmed the biological diagnosis by mycological, serological, and histological methods. In spite of receiving the appropriate treatment, the patient died 3 months later of cardiac insufficiency. We report here this additional case of Histoplasma endocarditis, by hoping to help rapid and accurate diagnosis of such infections in their early stages of development, in non-endemic areas. Keywords Histoplasma capsulatum * Endocarditis * Travel * Diagnosis