학술논문
Gonads directly regulate growth in teleosts
Document Type
Report
Author abstract
Author abstract
Author
Source
Proceedings of the National Academy of Sciences of the United States. July 10, 2012, Vol. 109 Issue 28, p11408, 5 p.
Subject
Language
English
ISSN
0027-8424
Abstract
In general, there is a relationship between growth and reproduction, and gonads are known to be important organs for growth, but direct evidence for their role is lacking. Here, using a fish model, we report direct evidence that gonads are endocrine organs equal to the pituitary in controlling body growth. Gonadal loss of function, gain of function, and rescue of growth were investigated in tilapia. Gonadectomy experiments were carried out in juvenile males and females. Gonadectomy significantly retarded growth compared with controls; however, this retardation was rescued by the implantation of extirpated gonads. Because gonads express growth hormone, it is possible that gonads control body growth through the secretion of growth hormone and/or other endocrine factors. We propose that gonads are integral players in the dynamic regulation of growth in teleosts. gonadal function | gonadal implantation | Mozambique tilapia doi/10.1073/pnas.1118704109