학술논문
Immunogenicity and safety of a meningococcal A conjugate vaccine in Africans
Document Type
Clinical report
Author
Sow, Samba O.; Okoko, Brown J.; Diallo, Aldiouma; Viviani, Simonetta; Borrow, Ray; Carlone, George; Tapia, Milagritos; Akinsola, Adebayo K.; Arduin, Pascal; Findlow, Helen; Elie, Cheryl; Haidara, Fadima Cheick; Adegbola, Richard A.; Diop, Doudou; Parulekar, Varsha; Chaumont, Julie; Martellet, Lionel; Diallo, Fatoumata; Idoko, Olubukola T.; Tang, Yuxiao; Plikaytis, Brian D.; Kulkarni, Prasad S.; Marchetti, Elisa; LaForce, F. Marc; Preziosi, Marie-Pierre
Source
The New England Journal of Medicine. June 16, 2011, Vol. 364 Issue 24, p2293, 12 p.
Subject
Language
English
ISSN
0028-4793
Abstract
Two studies were conducted in Africa to assess the immunogenicity and safety of a meningococcal A conjugate vaccine (PsA-TT). The data obtained revealed that the new PsA-TT exhibited a safety profile similar to that of a licensed polysaccharide vaccine but elicited a significantly stronger and more persistent response from functional antibodies against group A meningococcus.