학술논문
On genome-wide association studies for family-based designs: an integrative analysis approach combining ascertained family samples with unselected controls
Document Type
Report
Author
Source
American Journal of Human Genetics. April 9, 2010, Vol. 86 Issue 4, p573, 8 p.
Subject
Language
English
ISSN
0002-9297
Abstract
A novel family-based association tests (FBATs) is developed for ascertained samples that integrates unselected, genotyped controls from a population-based study into an over-all statistical test. The performance of the approach is demonstrated by an application to a genome-wide association studies (GWAS) of attention deficit hyperactivity disorder parent-offspring trios and publicly available controls.