부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.jpedsurg.2009.05.023 Byline: Francoise Schmitt (a), Gaelle Le Henaff (b), Hugues Piloquet (b), Marc D. Leclair (a), Albert David (c), Yves Heloury (a), Guillaume Podevin (a) Keywords: Hereditary pancreatitis; Chronic pancreatitis; Children Abstract: Hereditary pancreatitis (HP) is the primary etiology of chronic pancreatitis during childhood, progressing through recurrent episodes of acute pancreatitis and finally leading to pancreatic insufficiencies. Hereditary pancreatitis is because of mutations of the cationic trypsinogen (PRSS1) gene. Some other genes, such as SPINK1 or CFTR, have been associated with familial idiopathic chronic pancreatitis. The aim of our study was to clearly define diagnostic and therapeutic strategies for HP patients, through an analysis of our study group and a review of the literature. Author Affiliation: (a) Chirurgie infantile, HME, CHU de Nantes, France (b) Clinique Medicale Pediatrique, HME, CHU de Nantes, France (c) Genetique Medicale, PA[acute accent]le biologie, CHU de Nantes, France Article History: Received 10 March 2009; Revised 5 May 2009; Accepted 15 May 2009