학술논문
The prospect of vaccination against group a [beta]-hemolytic streptococci
Document Type
Academic Journal
Author
Source
Current Infectious Disease Reports. May, 2008, Vol. 10 Issue 3, p192, 8 p.
Subject
Language
English
ISSN
1523-3847
Abstract
Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specific vaccines, vaccines utilizing conserved M antigens, and vaccines based on other conserved surface-expressed or secreted antigens. Vaccine candidates in various stages of development offer promise for prevention of Group A streptococcal infections and their sequelae.