학술논문
Association between microdeletion and microduplication at 16p11.2 and autism
Document Type
Clinical report
Author
Weiss, Lauren A.; Shen, Yiping; Korn, Joshua M.; Arking, Dan E.; Miller, David T.; Fossdal, Ragnheidur; Saemundsen, Evald; Stefansson, Hreinn; Ferreira, Manuel A.R.; Green, Todd; Platt, Orah S.; Ruderfer, Douglas M.; Walsh, Chritopher A.; Altshuler, David; Chakravarti, Aravinda; Tanzi, Rudolph E.; Stefansson, Kari; Santangelo, Susan L.; Gusella, James F.; Sklar, Pamela; Bai-Lin Wu; Daly, Mark J.
Source
The New England Journal of Medicine. Feb 14, 2008, Vol. 358 Issue 7, p667, 9 p.
Subject
Language
English
ISSN
0028-4793
Abstract
A study to examine the genetic contribution of chromosomal abnormalities to autism, a heritable developmental disorder is conducted. Results indicate that a region of chromosome 16p11.2 influences susceptibility to autism when it is either deleted or duplicated.