학술논문
HLA and genomewide allele sharing in dizygotic twins
Document Type
Report
Author
Source
American Journal of Human Genetics. Dec 2006, Vol. 79 Issue 6, p1052, 7 p.
Subject
Language
English
ISSN
0002-9297
Abstract
Genome scans are conducted in large samples of dizygotic (DZ) twins from Australia and The Netherlands in order to estimate allele sharing in DZ twins and also to determine whether there is evidence of transmission distortion around the HLA locus or in other chromosomal regions. The results have shown that gene-mapping studies based on affected sibling pairs that include DZ pairs will not suffer from false-positive results due to loci involved in embryo survival.