학술논문
Tumor de células granulares de laringe. Descripción de dos casosGranular cell tumor of the larynx. Report of two cases
Document Type
TEXT
Author
Source
Subject
Language
Spanish; Castilian
Multiple languages
Multiple languages
Abstract
[ES] Introducción y objetivo: El tumor de células granulares es una neoplasia infrecuente, usualmente benigna que se puede originar en diferentes sitios anatómicos. El 50% de los casos se localizan en cabeza y cuello; la laringe solo se afecta entre el 3-10% de los casos. Existe controversia en cuanto a la etiología y el origen histológico. El tratamiento de elección es la cirugía. Descripción de los casos: Varón de 57 años de edad con disfonía de larga evolución. No presenta antecedentes de interés y en la exploración laríngea se observa una lesión glótica izquierda de aspecto benigno. Mujer de 45 años con disfonía de larga evolución, fumadora habitual que presenta una zona quística en tercio medio de cuerda vocal derecha que contacta con ligamento vocal. A ambos pacientes se les realiza microcirugía endolaringea para extirpación de lesiones y el resultado anatomopatológico es de tumor de células granulares. Discusión: Se realiza una revisión de la literatura observando que es un tumor extremadamente raro y más aún en la localización laríngea. El aspecto endoscópico laríngeo es de lesión benigna y el tratamiento de elección es la cirugía con márgenes amplios. Conclusiones: El tumor de células granulares es una neoplasia poco frecuente especialmente en laringe y debemos tenerlo en cuenta en el diagnóstico diferencial de las masas laríngeas. El tratamiento es quirúrgico con bajo índice de recurrencia y el riesgo de malignización es excepcional aunque esta descrito.
[EN] Introduction and objective: The granular cell tumor is an uncommon, usually benign neoplasm that may originate from different anatomical sites. 50% of cases are located in the head; the larynx is involved in 3-10% of the cases. Controversy exists as to the etiology and histological origin. Surgery is the treatment of the choice. Case description: Male patient 57 years old with longstanding hoarseness. On physical examination a benign looking lesion is found in the left glottis. 45 year old woman with longstanding hoarseness, habitual smoker. She shows a cystic area in the middle third of the right vocal fold reaching the vocal ligament. Both patients undergo laryngeal microsurgery to remove the lesions and pathologic report is granular cell tumor. Discussion: A review of the literature was performed noting that it is an extremely rare, specially in the larynx. The endoscopic appearance is that of a laryngeal benign lesion and its treatment of choice is surgery with wide margins. Conclusions: The granular cell tumor is a rare neoplasm especially in larynx that should be considered in the differential diagnosis of laryngeal masses. The treatment is surgery, with a low rate of recurrence and the risk of malignant transformation is exceptional though it is described.
[EN] Introduction and objective: The granular cell tumor is an uncommon, usually benign neoplasm that may originate from different anatomical sites. 50% of cases are located in the head; the larynx is involved in 3-10% of the cases. Controversy exists as to the etiology and histological origin. Surgery is the treatment of the choice. Case description: Male patient 57 years old with longstanding hoarseness. On physical examination a benign looking lesion is found in the left glottis. 45 year old woman with longstanding hoarseness, habitual smoker. She shows a cystic area in the middle third of the right vocal fold reaching the vocal ligament. Both patients undergo laryngeal microsurgery to remove the lesions and pathologic report is granular cell tumor. Discussion: A review of the literature was performed noting that it is an extremely rare, specially in the larynx. The endoscopic appearance is that of a laryngeal benign lesion and its treatment of choice is surgery with wide margins. Conclusions: The granular cell tumor is a rare neoplasm especially in larynx that should be considered in the differential diagnosis of laryngeal masses. The treatment is surgery, with a low rate of recurrence and the risk of malignant transformation is exceptional though it is described.