학술논문
Discovery of TRPA1 Antagonist GDC-6599: Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease
Document Type
Article
Author
Terrett, J.A.; Villemure, E.; Chen, H.; Shore, D.G.; Katavolos, P.; Hasselgren, C.; Laing, S.; Zhong, F.; Booler, H.; Cain, G.; Chou, C.; Fullerton, A.; Lepherd, M.; Stainton, S.; Torres, E.; Urban, K.; Yu, L.; Zhong, Y.; Kakiuchi-Kiyota, S.; Ly, J.Q.; Déry, M.; Larouche-Gauthier, R.; Beaumier, F.; Constantineau-Forget, L.; Grand-Maître, C.; Lépissier, L.; Ciblat, S.; Sturino, C.; Lee, W.P.; Suto, E.; Elstrott, J.; Gandham, V.; Joseph, V.; Johnson, K.; La, H.; Liu, L.; Mulder, T.; Brooks, M.; Stablein, A.; Chen, Y.; Hu, B.; Bao, L.; Chou, K.-J.; Lin, J.; Zhang, W.; Chen, J.; Chernov-Rogan, T.; Johnson, A.R.; Hackos, D.H.; Leahey, R.; Shields, S.D.; Riol-Blanco, L.; Balestrini, A.; Safina, B.S.; Volgraf, M.; Magnuson, S.
Source
In: Journal of Medicinal Chemistry . (Journal of Medicinal Chemistry, 14 March 2024, 67(5):3287-3306)
Subject
Language
English
ISSN
15204804
00222623
00222623