학술논문
Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of ((S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841)
Document Type
Article
Author
Fensome, A.; Dowty, M.E.; Efremov, I.V.; Gerstenberger, B.S.; Gopalsamy, A.; Saiah, E.; Wan, Z.-K.; Xing, L.; Yang, X.; Zhang, L.; Ambler, C.M.; Arnold, E.; Banker, M.E.; Brown, M.F.; Chrencik, J.; Flick, A.; Hayward, M.M.; Knafels, J.D.; Limburg, D.C.; Lin, D.; Pierce, B.S.; Sharma, R.; Trujillo, J.I.; Vajdos, F.F.; Vincent, F.; Yang, X.; Clark, J.D.; Hegen, M.; Jussif, J.; Lin, T.H.; Symanowicz, P.T.; Telliez, J.-B.; Hollingshead, B.D.
Source
In: Journal of Medicinal Chemistry . (Journal of Medicinal Chemistry, 11 October 2018, 61(19):8597-8612)
Subject
Language
English
ISSN
15204804
00222623
00222623