부산대학교 도서관

In the pharmaceutical industry, problems like counterfeit drugs, including vaccines, and their supply chain management problems like transparency, immutability, and traceability exist. In the case of vaccines, it becomes more difficult to standardize and detect fake vaccines because the public has less awareness and knowledge about vaccines. Moreover, the increase in online pharmacies gives more opportunities for counterfeiting vaccines to enter the authentic supply chain management system. We present transparent, immutable and secure vaccine supply chain (TISVSchain), a framework based on blockchain to handle the issues of counterfeited vaccines and vaccine supply chain problems like transparency, immutability, and traceability. Our proposed framework can run both on the private and public blockchain. We have implemented the framework on public blockchain by using remix ide and the smart contracts designed by solidity language run on very low gas cost. We also carried out several experiments by changing the number of nodes and their block time to evaluate the performance of our framework in terms of transaction per second (TPS), gas cost, and propagation delay. Our proposed framework improves the security by using offline unique account addresses in blockchain-based frameworks and improves the overall efficiency of the framework by keeping the gas cost low, finding a way to decrease the number of lost blocks to keep low propagation delay, and keeping high TPS value. TISVSchain shows us promising results to improve vaccine supply chain management’s overall performance, security, and efficiency.