학술논문

EMG-Informed Neuromusculoskeletal Models Accurately Predict Knee Loading Measured Using Instrumented Implants
Document Type
Periodical
Source
IEEE Transactions on Biomedical Engineering IEEE Trans. Biomed. Eng. Biomedical Engineering, IEEE Transactions on. 69(7):2268-2275 Jul, 2022
Subject
Bioengineering
Computing and Processing
Components, Circuits, Devices and Systems
Communication, Networking and Broadcast Technologies
Muscles
Load modeling
Loading
Electromyography
Stochastic processes
Knee
Biological system modeling
Biomechanics
Biomechanical simulation
neuromusculoskeletal models
electromyography
Language
ISSN
0018-9294
1558-2531
Abstract
Objective: Using a musculoskeletal modelling framework, we aimed to (1) estimate knee joint loading using static optimization (SO); (2) explore different calibration functions in electromyogram (EMG)-informed models used in estimating knee load; and (3) determine, when using an EMG-informed stochastic method, if the measured joint loadings are solutions to the muscle redundancy problem when investigating only the uncertainty in muscle forces. Methods : Musculoskeletal models for three individuals with instrumented knee replacements were generated. Muscle forces were calculated using SO, EMG-informed, and EMG-informed stochastic methods. Measured knee joint loads from the prostheses were compared to the SO and EMG-informed solutions. Root mean square error (RMSE) in joint load estimation was calculated, and the muscle force ranges were compared. Results : The RMSE ranged between 192-674 N, 152-487 N, and 7-108 N for the SO, the calibrated EMG-informed solution, and the best fit stochastic result, respectively. The stochastic method produced solution spaces encompassing the measured joint loading up to 98% of stance. Conclusion: Uncertainty in muscle forces can account for total knee loading and it is recommended that, where possible, EMG measurements should be included to estimate knee joint loading. Significance: This work shows that the inclusion of EMG-informed modelling allows for better estimation of knee joint loading when compared to SO.