학술논문

Clinical SiPM-Based MRI-Compatible SPECT: Preliminary Characterization
Document Type
Periodical
Source
IEEE Transactions on Radiation and Plasma Medical Sciences IEEE Trans. Radiat. Plasma Med. Sci. Radiation and Plasma Medical Sciences, IEEE Transactions on. 4(3):371-377 May, 2020
Subject
Nuclear Engineering
Engineered Materials, Dielectrics and Plasmas
Bioengineering
Computing and Processing
Fields, Waves and Electromagnetics
Collimators
Single photon emission computed tomography
Detectors
Magnetic resonance imaging
Cooling
Prototypes
Multimodal imaging
silicon photomultiplier (SiPM)
slit-slat collimator
Language
ISSN
2469-7311
2469-7303
Abstract
The initial characterization of the first single-photon emission computed tomography (SPECT) insert for simultaneous human brain imaging inside magnetic resonance imaging (MRI) is presented. The instrument features a novel multimini-slit-slat collimator and a static ring of 20 detectors. The scanner architecture is modular and represents the scale-up of a preclinical version whose MRI-compatibility has been already successfully demonstrated. The detectors are based on CsI(Tl) crystals (50 mm $\times $ 100 mm $\times $ 8 mm) coupled to arrays of silicon photomultipliers and ASIC readout for a total of 1440 channels. The transaxial field of view (FoV) is 20 cm by 9 cm in the axial direction. The experimental results show a sensitivity of 362 cps/MBq, an energy resolution of ~17% (at 140 keV), and a tomographic extrinsic resolution in the transaxial plane of ~8 mm across the whole FoV.