학술논문
Real-Time Epileptic Seizure Prediction Using AR Models and Support Vector Machines
Document Type
Periodical
Source
IEEE Transactions on Biomedical Engineering IEEE Trans. Biomed. Eng. Biomedical Engineering, IEEE Transactions on. 57(5):1124-1132 May, 2010
Subject
Language
ISSN
0018-9294
1558-2531
1558-2531
Abstract
This paper addresses the prediction of epileptic seizures from the online analysis of EEG data. This problem is of paramount importance for the realization of monitoring/control units to be implanted on drug-resistant epileptic patients. The proposed solution relies in a novel way on autoregressive modeling of the EEG time series and combines a least-squares parameter estimator for EEG feature extraction along with a support vector machine (SVM) for binary classification between preictal/ictal and interictal states. This choice is characterized by low computational requirements compatible with a real-time implementation of the overall system. Moreover, experimental results on the Freiburg dataset exhibited correct prediction of all seizures ($100 \%$ sensitivity) and, due to a novel regularization of the SVM classifier based on the Kalman filter, also a low false alarm rate.