학술논문

Real-Time Epileptic Seizure Prediction Using AR Models and Support Vector Machines
Document Type
Periodical
Source
IEEE Transactions on Biomedical Engineering IEEE Trans. Biomed. Eng. Biomedical Engineering, IEEE Transactions on. 57(5):1124-1132 May, 2010
Subject
Bioengineering
Computing and Processing
Components, Circuits, Devices and Systems
Communication, Networking and Broadcast Technologies
Epilepsy
Predictive models
Support vector machines
Electroencephalography
Support vector machine classification
Brain modeling
Data analysis
Patient monitoring
Parameter estimation
State estimation
Autoregressive (AR) models
EEG signals
epileptic seizure prediction
Kalman filtering
support vector machines (SVMs)
Language
ISSN
0018-9294
1558-2531
Abstract
This paper addresses the prediction of epileptic seizures from the online analysis of EEG data. This problem is of paramount importance for the realization of monitoring/control units to be implanted on drug-resistant epileptic patients. The proposed solution relies in a novel way on autoregressive modeling of the EEG time series and combines a least-squares parameter estimator for EEG feature extraction along with a support vector machine (SVM) for binary classification between preictal/ictal and interictal states. This choice is characterized by low computational requirements compatible with a real-time implementation of the overall system. Moreover, experimental results on the Freiburg dataset exhibited correct prediction of all seizures ($100 \%$ sensitivity) and, due to a novel regularization of the SVM classifier based on the Kalman filter, also a low false alarm rate.