학술논문

Live-Cell Imaging with Integrated Capacitive Sensor Arrays
Document Type
Conference
Source
2023 International Electron Devices Meeting (IEDM) Electron Devices Meeting (IEDM), 2023 International. :1-4 Dec, 2023
Subject
Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Engineered Materials, Dielectrics and Plasmas
Fields, Waves and Electromagnetics
Nuclear Engineering
Photonics and Electrooptics
Power, Energy and Industry Applications
Robotics and Control Systems
Signal Processing and Analysis
Integrated circuits
Microelectrodes
Microorganisms
Imaging
Sensors
Monitoring
Sensor arrays
Language
ISSN
2156-017X
Abstract
Capacitive imaging is a near-field sensing technique that detects changes in the dielectric properties and geometry of materials above a microelectrode array. Taking advantage of modern integrated circuits, dense capacitive sensing arrays can now be created at the scales of single biological cells. These non-optical imaging arrays offer intriguing possibilities for cell culture monitoring, offering low cost, portability, single-cell resolution, a wide field of view, and co-integration with multiple electrochemical sensing and stimulation modes. Here we review state-of-the-art examples of capacitive imaging arrays and present new demonstrations of all-electrical imaging of growing bacterial cultures.