학술논문

Standardization of Agnostic Learning Techniques in Neuroimaging: a Case Study in EEG
Document Type
Conference
Source
2022 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC) Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2022 IEEE. :1-4 Nov, 2022
Subject
Components, Circuits, Devices and Systems
Computing and Processing
Engineered Materials, Dielectrics and Plasmas
Nuclear Engineering
Photonics and Electrooptics
Signal Processing and Analysis
Neuroimaging
Visualization
Upper bound
Magnetic resonance imaging
Electroencephalography
Task analysis
Faces
Language
ISSN
2577-0829
Abstract
Over the last few years, the use of multivariate pattern analysis (MVPA) has been growing exponentially in cognitive neuroscience. This methodology offers the possibility to perform more detailed studies in electroencephalography (EEG) and other neuroimaging modalities. Usually, machine learning-based algorithms along with empirical out-of sample generalization approaches, e.g. K-fold cross validation (CV), are implemented. In this work we applied a validation approach based on resubstitution with upper bound correction to address the instability problem concerning limited sample sizes, particularly typical in neuroimaging, when estimating accuracy via CV. Moreover, a statistical assessment of the accuracies is conducted. To this end, the methodology underlying Statistical Agnostic Mapping (SAM) to perform spatial detection of regions of interest (ROIs) in neuromaging modalities, such as magnetic resonance imaging (MRI), has been applied to a temporal EEG study. Instead of estimating ROIs by means of a significance maps, the time points where trials are most significant are highlighted. The analyses were implemented on an EEG dataset obtained from 48 participants that performed a simple go-nogo task, in which they were presented names and faces. Here, we classified name and face perception at the subject level. The findings suggest that the use of resubstitution-based approaches can reduce the computational burden and obtain similar, albeit more conservative, results than CV.