학술논문
Smart Optode for 8-Wavelength Time-Gated Diffuse Optics
Document Type
Periodical
Author
Source
IEEE Journal of Selected Topics in Quantum Electronics IEEE J. Select. Topics Quantum Electron. Selected Topics in Quantum Electronics, IEEE Journal of. 30(1: Single-Photon Technologies and Applications):1-9 Jan, 2024
Subject
Language
ISSN
1077-260X
1558-4542
1558-4542
Abstract
We present the most compact (4 cm 3 ) time domain diffuse optical spectroscopy system, hosting 8 laser sources emitting at different wavelengths, a large area time-gated detector, and a time-to-digital converter. We tested the optode using standardized protocols, enlightening a high light harvesting capability and large penetration depth in detecting realistic optical inhomogeneities. We tested it also in vivo for the non-invasive assessment of blood parameters in a vascular occlusion test and for the detection of brain activation, demonstrating the optode capability to follow task-related hemodynamic changes even through a single measurement, with no need for averaging or filtering as instead needed with most available systems. The optode is thus a good candidate for next generation home-monitoring devices, thanks to its good performances, small dimension and potential low-cost.