학술논문

Advanced Phase-Retrieval for Stepping-Free X-Ray Dark-Field Computed Tomography
Document Type
Periodical
Source
IEEE Transactions on Medical Imaging IEEE Trans. Med. Imaging Medical Imaging, IEEE Transactions on. 42(10):2876-2885 Oct, 2023
Subject
Bioengineering
Computing and Processing
X-ray imaging
Computed tomography
Gratings
Crosstalk
Imaging
Demodulation
Detectors
image reconstruction
parameter estimation
signal analysis
x-rays
Language
ISSN
0278-0062
1558-254X
Abstract
Grating-based phase- and dark-field-contrast X-ray imaging is a novel technology that aims to extend conventional attenuation-based X-ray imaging by unlocking two additional contrast modalities. The so called phase-contrast and dark-field channels provide enhanced soft tissue contrast and additional microstructural information. Accessing this additional information comes at the expense of a more intricate measurement setup and necessitates sophisticated data processing. A big challenge for translating grating-based dark-field computed tomography to medical applications lies in minimizing the data acquisition time. While a continuously moving detector is ideal, it prohibits conventional phase stepping techniques that require multiple projections under the same angle with different grating positions. One solution to this problem is the so-called sliding window processing approach that is compatible with continuous data acquisition. However, conventional sliding window techniques lead to crosstalk-artifacts between the three image channels, if the projection of the sample moves too fast on the detector within a processing window. In this work we introduce a new interpretation of the phase retrieval problem for continuous acquisitions as a demodulation problem. In this interpretation, we identify the origin of the crosstalk-artifacts as partially overlapping modulation side bands. Furthermore, we present three algorithmic extensions that improve the conventional sliding-window-based phase retrieval and mitigate crosstalk-artifacts. The presented algorithms are tested in a simulation study and on experimental data from a human-scale dark-field CT prototype. In both cases they achieve a substantial reduction of the occurring crosstalk-artifacts.