학술논문
An Assessment of Ovarian Cancer Histotypes Across the African Diaspora
Document Type
article
Author
Sophia H. L. George; Ayodele Omotoso; Andre Pinto; Aisha Mustapha; Alex P. Sanchez-Covarrubias; Usman Aliyu Umar; Ali Bala Umar; Timothy Abiola Oluwasola; Clement Abu Okolo; Umeh Uchenna Anthony; Francis Ikechukwu Ukekwe; Maisaratu A. Bakari; Aminu M. C. Dahiru; Habiba Ibrahim Abdullahi; Bawa Ahmed Abimiku; Aisha Abdurrahman; Asmau Usman; Saad Aliyu Ahmed; Hadiza Abdullahi Usman; Abba Kabir; George Uchenna Eleje; Michael Emeka Chiemeka; Emily Nzeribe; Ikechukwu Nweke; SaiduAbubakar Kadas; Dauda E. Suleiman; Etim Ekanem; Umemmuo Maureen Uche; Jibrin Paul; Uzoma Maryrose Agwu; Felix O. Edegbe; Rose I. Anorlu; Adekunbiola Banjo; Kayode Olusegun Ajenifuja; Adegboyega Adisa Fawole; Ibrahim O. O. Kazeem; Francis Magaji; Olugbenga Silas; Boma Precious Athanasius; Nyengidiki Kennedy Tamunomie; Emem Bassey; Kunle Abudu; Ibrahim G. Ango; Kabiru Abdullahi; Ishak Lawal; Suleiman Aliyu Kabir; Victor Ekanem; Michael Ezeanochie; Usman Rahman Yahaya; Melissa Nicole Castillo; Vishal Bahall; Vikash Chatrani; Ian Brambury; Saida Bowe; Darron Halliday; George Bruney; Raleigh Butler; Camille Ragin; Folakemi Odedina; Srikar Chamala; Matthew Schlumbrecht; Bala Audu
Source
Frontiers in Oncology, Vol 11 (2021)
Subject
Language
English
ISSN
2234-943X
Abstract
ObjectiveOvarian cancer in Black women is common in many West African countries but is relatively rare in North America. Black women have worse survival outcomes when compared to White women. Ovarian cancer histotype, diagnosis, and age at presentation are known prognostic factors for outcome. We sought to conduct a preliminary comparative assessment of these factors across the African diaspora.MethodsPatients diagnosed with ovarian cancer (all histologies) between June 2016-December 2019 in Departments of Pathology at 25 participating sites in Nigeria were identified. Comparative population-based data, inclusive of Caribbean-born Blacks (CBB) and US-born Blacks (USB), were additionally captured from the International Agency for Research on Cancer and Florida Cancer Data Systems. Histology, country of birth, and age at diagnosis data were collected and evaluated across the three subgroups: USB, CBB and Nigerians. Statistical analyses were done using chi-square and student’s t-test with significance set at p