학술논문

Inborn Errors of Immunity Causing Pediatric Susceptibility to Fungal Diseases
Document Type
article
Source
Journal of Fungi, Vol 9, Iss 2, p 149 (2023)
Subject
inborn errors of immunity
primary immunodeficiency
fungi
mycoses
invasive fungal disease
superficial fungal disease
Biology (General)
QH301-705.5
Language
English
ISSN
2309-608X
Abstract
Inborn errors of immunity are a heterogeneous group of genetically determined disorders that compromise the immune system, predisposing patients to infections, autoinflammatory/autoimmunity syndromes, atopy/allergies, lymphoproliferative disorders, and/or malignancies. An emerging manifestation is susceptibility to fungal disease, caused by yeasts or moulds, in a superficial or invasive fashion. In this review, we describe recent advances in the field of inborn errors of immunity associated with increased susceptibility to fungal disease.