학술논문
Impact of malnutrition on mortality and neurological recovery of older patients with spinal cord injury
Document Type
article
Author
Koji Tamai; Hidetomi Terai; Hiroaki Nakamura; Noriaki Yokogawa; Takeshi Sasagawa; Hiroaki Nakashima; Naoki Segi; Sadayuki Ito; Toru Funayama; Fumihiko Eto; Akihiro Yamaji; Kota Watanabe; Junichi Yamane; Kazuki Takeda; Takeo Furuya; Atsushi Yunde; Hideaki Nakajima; Tomohiro Yamada; Tomohiko Hasegawa; Yoshinori Terashima; Ryosuke Hirota; Hidenori Suzuki; Yasuaki Imajo; Shota Ikegami; Masashi Uehara; Hitoshi Tonomura; Munehiro Sakata; Ko Hashimoto; Yoshito Onoda; Kenichi Kawaguchi; Yohei Haruta; Nobuyuki Suzuki; Kenji Kato; Hiroshi Uei; Hirokatsu Sawada; Kazuo Nakanishi; Kosuke Misaki; Akiyoshi Kuroda; Gen Inoue; Kenichiro Kakutani; Yuji Kakiuchi; Katsuhito Kiyasu; Hiroyuki Tominaga; Hiroto Tokumoto; Yoichi Iizuka; Eiji Takasawa; Koji Akeda; Norihiko Takegami; Haruki Funao; Yasushi Oshima; Takashi Kaito; Daisuke Sakai; Toshitaka Yoshii; Tetsuro Ohba; Bungo Otsuki; Shoji Seki; Masashi Miyazaki; Masayuki Ishihara; Seiji Okada; Shiro Imagama; Satoshi Kato
Source
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract This retrospective cohort study established malnutrition’s impact on mortality and neurological recovery of older patients with cervical spinal cord injury (SCI). It included patients aged ≥ 65 years with traumatic cervical SCI treated conservatively or surgically. The Geriatric Nutritional Risk Index was calculated to assess nutritional-related risk. Overall, 789 patients (mean follow-up: 20.1 months) were examined and 47 had major nutritional-related risks on admission. One-year mortality rate, median survival time, neurological recovery, and activities of daily living (ADL) at 1 year post-injury were compared between patients with major nutrition-related risk and matched controls selected using 1:2 propensity score matching to adjust for age, pre-traumatic neurological impairment, and activity. In the Kaplan–Meier analysis, the median survival times were 44.9 and 76.5 months for patients with major nutrition-related risk and matched controls, respectively (p = 0.015). Matched controls had more individuals with a neurological improvement of American Spinal Injury Association Impairment Scale ≥ 1 grade (p = 0.039) and independence in ADL at 1 year post-injury than patients with major nutrition-related risk (p