학술논문
4D analysis of malaria parasite invasion offers insights into erythrocyte membrane remodeling and parasitophorous vacuole formation
Document Type
article
Author
Source
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Here, Geoghegan, Evelyn et al. provide a lattice light-sheet microscopy based 4D imaging pipeline to quantitatively investigate Plasmodium spp. invasion and show that the nascent parasitophorous vacuole is predominantly formed from host’s erythrocyte membrane and undergoes continuous remodeling throughout invasion.