학술논문
Incidence rate and predictors of COVID-19 in the two largest cities of Burkina Faso - prospective cohort study in 2021 (ANRS-COV13)
Document Type
article
Author
Nongodo Firmin Kaboré; Samiratou Ouédraogo; Ariane Kamga Mamguem; Isidore Tiandiogo Traoré; Dramane Kania; Hermann Badolo; Guillaume Sanou; Amariane Koné; Mimbouré Yara; Thérèse Kagoné; Esperance Ouédraogo; Blahima Konaté; Rachel Médah; Nathalie de Rekeneire; Armel Poda; Arnaud Eric Diendéré; Boukary Ouédraogo; Oumar Billa; Gilles Paradis; Tienhan Sandrine Dabakuyo-Yonli; Halidou Tinto
Source
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-11 (2023)
Subject
Language
English
ISSN
1471-2334
Abstract
Abstract Background Early data on COVID-19 (based primarily on PCR testing) indicated a low burden in Sub-Saharan Africa. To better understand this, this study aimed to estimate the incidence rate and identify predictors of SARS-CoV-2 seroconversion in the two largest cities of Burkina Faso. This study is part of the EmulCOVID-19 project (ANRS-COV13). Methods Our study utilized the WHO Unity protocol for cohort sero-epidemiological studies of COVID-19 in general population. We conducted random sampling stratified by age group and sex. Individuals aged 10 years and older in the cities of Ouagadougou and Bobo-Dioulasso, Burkina Faso were included and surveyed at 4 time points, each 21 days apart, from March 3 to May 15, 2021. WANTAI SARS-CoV-2 Ab ELISA serological tests were used to detect total antibodies (IgM, IgG) in serum. Predictors were investigated using Cox proportional hazards regression. Results We analyzed the data from 1399 participants (1051 in Ouagadougou, 348 in Bobo-Dioulasso) who were SARS-CoV-2 seronegative at baseline and had at least one follow-up visit. The incidence rate of SARS-CoV-2 seroconversion was 14.3 cases [95%CI 13.3–15.4] per 100 person-weeks. The incidence rate was almost three times higher in Ouagadougou than in Bobo-Dioulasso (Incidence rate ratio: IRR = 2.7 [2.2–3.2], p