학술논문

Pneumococcal disease burden from an Indian perspective: Need for its prevention in pulmonology practice
Document Type
article
Source
Lung India, Vol 36, Iss 3, Pp 216-225 (2019)
Subject
Chronic obstructive pulmonary disease
community-acquired pneumonia
comorbidity
mortality
pneumococcal conjugate vaccine
Streptococcus pneumoniae
Diseases of the respiratory system
RC705-779
Language
English
ISSN
0970-2113
0974-598X
Abstract
Globally, pneumococcal diseases are a significant public health concern. They are preventable and frequently occur among older adults. Major risk factors for the disease are extremes of age, alcohol intake, smoking, air pollution, and comorbid conditions (diabetes, chronic obstructive pulmonary disease, chronic kidney disease, liver disease, and heart disease). Risk factors, coupled with limited disease-burden data and the emergence of antibiotics resistance, are hindering the effective management of the disease in older adults. Various global guidelines recommend pneumococcal vaccines for the prevention of pneumococcal diseases, as they reduce disease burden, hospitalization, and mortality rates among patients with comorbid conditions. Besides being an integral part of childhood immunization, these vaccines are advocated by various Indian healthcare bodies/groups for older and younger adults with certain medical conditions. The article presents an overview of the closed-door discussion by the Indian pulmonary experts on the scientific evidence and clinical practice followed for the prevention of pneumococcal disease in India.