학술논문

Massive hypertriglyceridemia associated with paclitaxel; a case report
Document Type
article
Source
Gynecologic Oncology Reports, Vol 42, Iss , Pp 101030- (2022)
Subject
Paclitaxel
Hypertriglyceridemia
Fallopian tube carcinoma
Gynecology and obstetrics
RG1-991
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Language
English
ISSN
2352-5789
Abstract
This report describes a patient who developed massive hypertriglyceridemia (12,488 mg/dL or 141 mmol/L) during paclitaxel and carboplatin adjuvant chemotherapy for high grade serous fallopian tube carcinoma. Paclitaxel was thought to be the causative agent and she had normal triglyceride levels following a change to carboplatin and gemcitabine. To our knowledge, this is the highest reported triglyceride level associated with paclitaxel. Measurement of serum lipids should be considered in individuals receiving taxane chemotherapy, especially in those with type 2 diabetes mellitus or a history of dyslipidemia.