학술논문

The role of natural resistance factors in the development of inflammatory complications in patients with closed thoracic trauma
Document Type
article
Source
Актуальні проблеми сучасної медицини, Vol 4, Pp 22-29 (2019)
Subject
closed chest injury
inflammatory complications
diagnosis
lysozyme
Medicine
Language
English
Russian
Ukrainian
ISSN
2617-409X
Abstract
Summary. In recent years, the upward trend in closed severe chest injuries has increased. Closed chest injury with fractures of the ribs is often accompanied by the occurrence of purulent-inflammatory complications. So, the ability of blood serum to lysis Escherichia coli (bactericidal activity of blood serum), micrococcus (indicator of lysozyme content), bacillus subtilis (indicator of beta-lysine content) in 54 patients with a closed chest injury was studied. The indicators of factors of natural resistance were compared with those of 40 healthy people. In addition, the indicators of patients whose trauma proceeded with and without an inflammatory complication were compared with each other. Inflammatory complications in the form of post-traumatic pleurisy and pneumonia were observed in 34 (62.9%) of the examined patients with fractures of 1-3 ribs. In patients with these injuries, we revealed a slight decrease in the bactericidal activity of blood serum: on the first day in the group of patients with a smooth flow to 75.92 + 3.22%, and in the group of patients with complication of the trauma, the inflammatory process (pleurisy, pneumonia) to 72, 83 + 2.65%. On the second day, in the first group, BABS decreases even more to 70.79 + 3.11%, and on the second day it increases to 87.32 + 1.91% (p