학술논문
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma
Document Type
article
Author
Stephen T. Magill; Harish N. Vasudevan; Kyounghee Seo; Javier E. Villanueva-Meyer; Abrar Choudhury; S. John Liu; Melike Pekmezci; Sarah Findakly; Stephanie Hilz; Sydney Lastella; Benjamin Demaree; Steve E. Braunstein; Nancy Ann Oberheim Bush; Manish K. Aghi; Philip V. Theodosopoulos; Penny K. Sneed; Adam R. Abate; Mitchel S. Berger; Michael W. McDermott; Daniel A. Lim; Erik M. Ullian; Joseph F. Costello; David R. Raleigh
Source
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Subject
Language
English
ISSN
2041-1723
Abstract
Meningiomas are heterogeneous tumours. Here, the authors analysed genetic, epigenetic, and transcriptomic features across spatially-distinct meningioma samples to identify molecular programs underlying tumorigenesis that can be detected preoperatively using magnetic resonance imaging.