학술논문

Accuracy of quantitative ultrasound parameters in the diagnosis of osteoporosis
Document Type
research-article
Source
Open Medicine. 5(4):478-485
Subject
Osteoporosis
Quantitative ultrasound
speed of sound
broadband ultrasound attenuation
T-Score
DXA
bone mineral density
Language
English
ISSN
2391-5463
Abstract
Quantitative ultrasound (QUS) is of increasing interest for evaluation of osteoporosis because, compared with dual-energy X-ray absorptiometry (DXA), it is portable, less expensive, and radiation-free. The aim of our study was to determine the sensitivity, specificity, and cut-off values of quantitative ultrasound parameters in identifying patients with osteoporosis compared to the World Health Organization (WHO) standard definition. We performed a cross-sectional investigational study of 73 subjects, and determined total hip and lumbar spine T-scores by dual-energy X-ray absorptiometry (DXA) (Prodigy Advance Lunar-GE). The QUS parameters (broadband ultrasound attenuation [BUA], speed of sound, bone mineral density, the stiffness index, and QUS T-score) were determined with Sahara Hologic equipment. The AUC was 0.81 (95% CI 0.67–0.95, p 50%) for all QUS parameters in both groups, (2-tailed, p