학술논문

新疆阿魏化学成分及药理活性研究进展 / Chemical constituents and pharmacological activities of Ferula sinkiangensis K.M. Shen:research advances
Document Type
Academic Journal
Source
国际药学研究杂志 / Journal of International Pharmaceutical Research. 44(6):495-499
Subject
新疆阿魏
资源分布
化学成分
指纹图谱
药理活性
Ferula sinkiangensis K.M. Shen
resource distribution
chemical constituents
fingerprints
pharmacological ac-tivities
Language
Chinese
ISSN
1674-0440
Abstract
新疆阿魏(Ferula sinkiangensis K.M.Shen)是分布在新疆北部的濒危民族植物药,主要含有倍半萜香豆素、含硫化合物、多糖和芳香族类等多种有效化学成分.目前多采用色谱技术建立指纹图谱实现质量控制.原植物药和特征化合物都具有抑菌、杀虫、抗过敏、抗肿瘤等广泛药理作用.本文主要从资源现状、化学成分、指纹图谱和药理活性等方面对国内外新疆阿魏的研究状况进行综述,为其系统化研究、有效质量控制和高效开发利用提供参考.
Ferula sinkiangensis K.M. Shen is a kind of endangered national plant medicine in the northern of Xinjiang,China. It mainly contains sesquiterpene coumarins,sulfides,polysaccharides,aromatic compounds and other effective chemical constitu-tions;Chromatography is used to build the fingerprint and to control the medicine quality in most cases. Both raw plant medicine and specific compounds possess pharmacologic activities such as antibacterial,insecticidal,anti-allergic,and antitumor properties. The present paper summarizes the resource distribution,chemical constituents,fingerprints and pharmacological activities of F. sinkian-gensis,to provide reference for its systematic research,effective quality control and efficient development and utilization.