부산대학교 도서관

Objectives: Studies have associated the long-term exposure to ambient particulates with mortality from various types of disease, including kidney disease. However, few studies integrating the relationship between ambient air quality and the mortality risk from kidney disease. The objective of this study is to evaluate this association using systematic literature review to provide empirical references for future research. Methods: Mesh term and free-text words were used for literature search. Articles were retrieved from electronic databases including PubMed, Cochrane Library, ProQuest, EMBASE, and Airiti Library. A total of 163 articles published before June 2022 met the search criteria. After screening the abstract, title, and main text of the studies to delete repetitions, we identified five studies eligible for the qualitative synthesis. Each study was appraised using the CASP-Cohort checklist and Oxford CEBM. Results: We examined the data in these five studies and found that the hazard ratio of mortality from dialysis ranged 1.33-3.78 for population with long-term exposure to NO_2. A study also found that the elderly patients with dialysis exposing to high levels of PM_(2.5) for 7 years were also at an elevated hazard of deaths. Conclusions: These studies showed that long-term exposure to NO_2 and PM_(2.5) might associate with an increased hazard of deaths from dialysis. However, these studies were conducted based on the outdoor air quality. Research based on indoor air quality and experimental study are required to verify the association with the mortality risk.