학술논문
GATA6 promotes fibrotic repair of tracheal injury through NLRP3 inflammasome-mediated epithelial pyroptosis
Document Type
Article
Author
Source
In International Immunopharmacology October 2023 123
Subject
Language
ISSN
1567-5769
Abstract
Highlights •GATA6 and NLRP3 inflammasome are critically upregulated in tracheal injury.•GATA6 drives NLRP3 inflammasome-mediated epithelial pyroptosis to promote the fibrotic repair of tracheal injury.•GATA6 may be a potential biological therapeutic target for tracheal injury and associated stenosis.