학술논문
Edaravone Dexborneol protects against blood-brain barrier disruption following cerebral ischemia/reperfusion by upregulating pericyte coverage via vitronectin-integrin and PDGFB/PDGFR-β signaling
Document Type
Article
Author
Source
In Free Radical Biology and Medicine 20 November 2024 225:758-766
Subject
Language
ISSN
0891-5849
Abstract
@@@@Highlights •Brain cytoprotection therapies following I/R injury have become an emerging interest.•Pericytes were vulnerable in early ischemia.•We aimed to explore Eda.B's protective effect on pericyte loss and its mechanisms.•PDGFB/PDGFR-β involved in the protection of Eda.B against pericyte injury after I/R.•VTN-α5 involved in the protection of Eda.B against pericyte injury after I/R.