학술논문
Curcumin supplementation alleviates hepatic fat content associated with modulation of gut microbiota-dependent bile acid metabolism in patients with nonalcoholic simple fatty liver disease: a randomized controlled trial
Document Type
Article
Author
He, Youming ; Chen, Xiaobing ; Li, Yongchun ; Liang, Yunyi ; Hong, Ting ; Yang, Jie ; Cao, Zhuo ; Mai, Haiyan ; Yao, Jiale ; Zhang, Tong ; Wu, Kaize ; Zou, Jun ; Feng, Dan
Source
In The American Journal of Clinical Nutrition July 2024 120(1):66-79
Subject
Language
ISSN
0002-9165
Abstract
Conclusions Improvements in gut microbiota-dependent BA metabolism and TGR5 activation after 24-wk curcumin intervention were associated with a reduction in hepatic fat content in patients with NASFL, providing evidence that curcumin is a potential nutritional therapy for NASFL.The trial was registered at www.chictr.org.cn as ChiCTR2200058052.