학술논문
Association of antimüllerian hormone levels with menstrual-cycle type and dysmenorrhea in young asymptomatic women.
Document Type
Article
Source
Subject
*ANTI-Mullerian hormone
*MENSTRUAL cycle
*DYSMENORRHEA
*DISEASES in women
*ORAL contraceptives
*BLOOD serum analysis
*CROSS-sectional method
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Language
ISSN
0015-0282
Abstract
Objective To examine the association between antimüllerian hormone (AMH) levels and menstrual-cycle and lifestyle characteristics among young Japanese women. Design Cross-sectional study. Setting University. Patient(s) Female students aged 20–22 years (n = 65) who had never used oral contraceptives. Intervention(s) Participants completed a questionnaire on reproductive and lifestyle characteristics, and kept a menstrual-cycle diary for 5 consecutive months. Serum AMH was measured once during the study period. Main Outcome Measure(s) Serum AMH concentration. Result(s) Compared with women with very mild menstrual pain, serum AMH concentration was 49.6% (95% CI 6.5%–72.8%) lower among women with severe menstrual pain. Higher AMH concentration was associated with irregular menstrual cycles. Even after adjusting for menstrual-cycle regularity and its interaction, more-severe menstrual pain was associated with significantly lower AMH concentration. Conclusion(s) Circulating AMH concentration was significantly lower among young Japanese women who had more-severe menstrual pain. Underlying physiological mechanisms need to be addressed in future studies. [ABSTRACT FROM AUTHOR]